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This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. Alternative splicing results in several transcript variants.
2900022I03Rik; a disintegrin and metallopeptidase domain 22; a disintegrin and metalloprotease domain (ADAM) 22; a disintegrin and metalloprotease domain 22; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 22; ADAM; ADAM 22; ADAM metallopeptidase domain 22; Adam22; ADAMs; AI854032; Disintegrin and metalloproteinase domain-containing protein 22; MDC2; metalloendopeptidases; Metalloproteinase-disintegrin ADAM22-3; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2; MGC149832
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