Aggrecan Antibodies

Antibodies that detect Aggrecan can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Aggrecan in Human, Rat, Mouse, Rabbit and Porcine samples. Our Aggrecan... Antibodies that detect Aggrecan can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Aggrecan in Human, Rat, Mouse, Rabbit and Porcine samples. Our Aggrecan polyclonal, monoclonal and recombinant monoclonal... Antibodies that detect Aggrecan can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Aggrecan in Human, Rat, Mouse, Rabbit and Porcine samples. Our Aggrecan polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment to confirm specificity to Aggrecan. Find the Aggrecan antibody that fits your needs. Choose from 1 of 18 Aggrecan antibodies, which have been validated in experiments with 319 publications and 87 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other... Antibodies that detect Aggrecan can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Aggrecan in Human, Rat, Mouse, Rabbit and Porcine samples. Our Aggrecan polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment to confirm specificity to Aggrecan. Find the Aggrecan antibody that fits your needs. Choose from 1 of 18 Aggrecan antibodies, which have been validated in experiments with 319 publications and 87 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

Aggrecan also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1 is a protein that is encoded by the ACAN gene. The encoded protein is an integral part of the extracellular matrix in cartilaginous tissue and it withstands compression in cartilage. The human form of the protein is 2316 amino acids long (approximately 250 kDa) and can be expressed in multiple isoforms due to alternative splicing. Aggrecan exhibits a bottlebrush structure, in which chondroitin sulfate and keratan sulfate chains are attached to an extended protein core. The synthesis and degradation of aggrecan are being investigated for their roles in cartilage deterioration during joint injury, disease, and aging. It contains three interglobular domains (IGDs), G1, G2, and G3 that are involved in aggregation, hyaluronan binding, cell adhesion, and chondrocyte apoptosis. Aggrecan fragments from articular cartilage are released into the synovial fluid at all stages of human osteoarthritis as a result of cleavage by aggrecanase and MMP activity. Antibodies BC-3 and BC-4 can be used to detect these neo epitopes of Aggrecanase (ARGSVXXX) and MMP (XXXVDIPEN), respectively.

同义词

ACAN; Agc; Agc1; AGCAN; aggrecan; aggrecan 1; aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122); aggrecan core protein; Aggrecan core protein 2; aggrecan CS2 domain; aggrecan epidermal growth factor-like domain-1; aggrecan G2 domain; aggrecan interglobular domain; aggrecan keratan sulfate domain; aggrecan, structural proteoglycan of cartilage; articular cartilage aggrecan precursor; b2b183Clo; cartilage aggregating proteoglycan; cartilage-specific proteoglycan core protein; Chondroitin sulfate proteoglycan 1; chondroitin sulfate proteoglycan core protein 1; cmd; CSPCP; CSPG1; CSPGCP; high density cartilage proteoglycan; large aggregating cartilage proteoglycan core protein; large aggregating proteoglycan; large aggregating proteoglycan, antigen; MSK16; SEDK

Aggrecan Antibodies

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