Antibodies that detect APAF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target APAF1 in Human, Mouse, Rat and Zebrafish samples. Our APAF1 polyclonal, monoclonal and...Antibodies that detect APAF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target APAF1 in Human, Mouse, Rat and Zebrafish samples. Our APAF1 polyclonal, monoclonal and recombinant monoclonal antibodies are...Antibodies that detect APAF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target APAF1 in Human, Mouse, Rat and Zebrafish samples. Our APAF1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to APAF1. Find the APAF1 antibody that fits your needs. Choose from 1 of 24 APAF1 antibodies, which have been validated in experiments with 7 publications and 59 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications....
Antibodies that detect APAF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target APAF1 in Human, Mouse, Rat and Zebrafish samples. Our APAF1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to APAF1. Find the APAF1 antibody that fits your needs. Choose from 1 of 24 APAF1 antibodies, which have been validated in experiments with 7 publications and 59 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
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