靶标信息
Multisubunit vacuolar-type proton pumps, or H(+)-ATPases, acidify various intracellular compartments, such as vacuoles, clathrin-coated and synaptic vesicles, endosomes, lysosomes, and chromaffin granules. H(+)-ATPases are also found in plasma membranes of specialized cells, where they play roles in urinary acidification, bone resorption, and sperm maturation. Multiple subunits form H(+)-ATPases, with proteins of the V1 class hydrolyzing ATP for energy to transport H+, and proteins of the V0 class forming an integral membrane domain through which H+ is transported. ATP6V0E2 encodes an isoform of the H(+)-ATPase V0 e subunit, an essential proton pump component.
同义词
0610006O14Rik; ATP6V0E2; ATP6V0E2L; ATPase H+ transporting V0 subunit e2; ATPase, H+ transporting V0 subunit e2; ATPase, H+ transporting, lysosomal V0 subunit E2; ATPase, H+ transporting, lysosomal, V0 subunit E; ATPase, H+ transporting, V0 subunit E; C7orf32; H+-ATPase e2 subunit; lysosomal 9 kDa H(+)-transporting ATPase V0 subunit e2; NM9.2; similar to ATPase, H+ transporting, V0 subunit; vacuolar proton pump subunit e 2; vacuolar proton-ATPase subunit; V-ATPase subunit e 2; V-type proton ATPase subunit e 2