Antibodies that detect BBS5 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Dot Blot. These antibodies target BBS5 in Human, Mouse and Rat samples. Our BBS5 monoclonal, polyclonal and recombinant monoclonal...Antibodies that detect BBS5 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Dot Blot. These antibodies target BBS5 in Human, Mouse and Rat samples. Our BBS5 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and...Antibodies that detect BBS5 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Dot Blot. These antibodies target BBS5 in Human, Mouse and Rat samples. Our BBS5 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the BBS5 antibody that fits your needs. Choose from 1 of 14 BBS5 antibodies, which have been validated in experiments with 42 publications and 38 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen...
Antibodies that detect BBS5 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Dot Blot. These antibodies target BBS5 in Human, Mouse and Rat samples. Our BBS5 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the BBS5 antibody that fits your needs. Choose from 1 of 14 BBS5 antibodies, which have been validated in experiments with 42 publications and 38 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.
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