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Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.
1200005K12Rik; antigen identified by monoclonal antibody F8; AU; Auberger B antigen; basal cell adhesion molecule; basal cell adhesion molecule (Lu and Au blood groups); basal cell adhesion molecule (Lutheran blood group); basal cell adhesion molecule Lutheran blood group; BCAM; B-CAM; B-CAM cell surface glycoprotein; B-cell adhesion molecule; CD239; F8/G253 antigen; glycoprotein 95kDa; Gplu; LU; lutheran antigen; Lutheran blood group; Lutheran blood group (Auberger b antigen included); Lutheran blood group glycoprotein; Lutheran blood group variant LUGA; lutheran glycoprotein; MSK19
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