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This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described.
Actin regulatory protein CAP-G; actin-capping protein GCAP39; actin-regulatory protein CAP-G; AFCP; Capg; capping actin protein, gelsolin like; capping protein (actin filament), gelsolin-like; epididymis secretory protein Li 66; gCap39; gelsolin-like capping protein; HEL-S-66; macrophage capping protein; macrophage-capping protein; mbh1; MCP; myc basic motif homolog 1
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