Antibodies that detect CD42b can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target CD42b in Human, Mouse, Porcine and Rat samples. Our CD42b monoclonal, polyclonal and...Antibodies that detect CD42b can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target CD42b in Human, Mouse, Porcine and Rat samples. Our CD42b monoclonal, polyclonal and recombinant monoclonal...Antibodies that detect CD42b can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target CD42b in Human, Mouse, Porcine and Rat samples. Our CD42b monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the CD42b antibody that fits your needs. Choose from 1 of 51 CD42b antibodies, which have been validated in experiments with 52 publications and 76 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody...
Antibodies that detect CD42b can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target CD42b in Human, Mouse, Porcine and Rat samples. Our CD42b monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the CD42b antibody that fits your needs. Choose from 1 of 51 CD42b antibodies, which have been validated in experiments with 52 publications and 76 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. CD42b expression and activation seems to be regulated by VEGF and PDGF. CD42b composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis. Further, CD42b antigen is expressed on platelets and on megakaryocytes in bone marrow. Several polymorphisms and mutations have been described in the CD42b, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease.
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party
scientific content. Neither the content nor the BenchSci technology and processes for
selection have been evaluated by us; we are providing them as-is and without warranty of any kind,
including for use or application of the Thermo Fisher Scientific products presented.