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This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
alpha-type CGRP; CA; Cal1; CAL6; CALC; Calc1; Calca; calcitonin; calcitonin 1; Calcitonin carboxyl-terminal peptide; Calcitonin gene-related peptide 1; calcitonin gene-related peptide I; calcitonin related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; calcitonin; calcitonin gene-related peptide 1; calcitonin-related polypeptide alpha; CCALCI; CCP; Cgrp; CGRP1; CGRP-1; CGRP-I; Ct; Ctn; Katacalcin; KC; MGC126648; PCT; PDN-21; prepro-alpha-calcitonin gene-related peptide; RAT calcitonin; RATCAL6
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