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CMBL is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom.
2310016A09Rik; Ab2-225; carboxymethylenebutenolidase homolog; carboxymethylenebutenolidase homolog (Pseudomonas); carboxymethylenebutenolidase-like (Pseudomonas); CMBL; JS-1; Liver regeneration-related protein LRRG072; RGD1306952
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