Antibodies that detect CTLA-4 (CD152) can be used in several scientific applications, including Flow Cytometry, Western Blot, ELISA, Immunohistochemistry (Paraffin) and Blocking assay. These antibodies target CTLA-4 (CD152) in Human, Mouse, Rhesus Monkey, Rat and Cynomolgus Monkey samples. Our CTLA-4 (CD152) monoclonal, polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Mouse, Rabbit, Armenian Hamster, Goat, Rat and Syrian Hamster. These antibodies have been verified by Cell treatment to confirm specificity to CTLA-4 (CD152). Find the CTLA-4 (CD152) antibody that fits your needs. Choose from 1 of 81 CTLA-4 (CD152) antibodies, which have been validated in experiments with 207 publications and 168 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
CD152; CD152 antigen; CTLA-4; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; ICOS