DACT3 Antibodies

Antibodies that detect DACT3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target DACT3 in Human, Mouse and Rat samples. Our DACT3 polyclonal antibodies are developed in Rabbit... Antibodies that detect DACT3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target DACT3 in Human, Mouse and Rat samples. Our DACT3 polyclonal antibodies are developed in Rabbit and Goat. Find the DACT3 antibody that fits your... Antibodies that detect DACT3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target DACT3 in Human, Mouse and Rat samples. Our DACT3 polyclonal antibodies are developed in Rabbit and Goat. Find the DACT3 antibody that fits your needs. Choose from 1 of 5 DACT3 antibodies, which have been validated in experiments with 5 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to... Antibodies that detect DACT3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target DACT3 in Human, Mouse and Rat samples. Our DACT3 polyclonal antibodies are developed in Rabbit and Goat. Find the DACT3 antibody that fits your needs. Choose from 1 of 5 DACT3 antibodies, which have been validated in experiments with 5 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact3, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact3 is expressed in the ventral region of maturing somites, limb bud and branchial arch mesenchyme, embryonic CNS, and the adult brain. Recent evidence shows that Dact3 acts as a negative regulator Wnt/beta-catenin signaling that is repressed at the transcriptional level in colorectal cancer and this repression is associated with bivalent histone modifications. This repression can be reversed by pharmacological agents that targets both histone methylation and deacetylation, suggesting that Dact3 may be a potential target for therapeutic treatment of this cancer. At least three isoforms of Dact3 are known to exist.

Synonyms

Antagonist of beta-catenin Dapper homolog 3; arginine-rich region 1 protein; dact 3; Dact3; Dapper antagonist of catenin 3; dapper homolog 3; dapper homolog 3, antagonist of beta-catenin (xenopus); dapper, antagonist of beta-catenin, homolog 3; DAPPER3; dishevelled binding antagonist of beta catenin 3; dishevelled-binding antagonist of beta-catenin 3; EG666671; naa-3; RGD1563892; RRR1

DACT3 Antibodies

Target Information

Synonyms

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