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Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase; ARS; Dcps; DCS1; DCS-1; decapping enzyme, scavenger; decapping scavenger enzyme; heat shock-like protein 1; HINT5; HINT-5; Hint-related 7meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; histidine triad protein member 5; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; HSL1; HSPC015; m7GpppX diphosphatase; mRNA decapping enzyme; scavenger mRNA-decapping enzyme DcpS
100 µL
100 µL
100 µL
100 µL
100 µL
100 µg
100 µg
100 µL
10 µL
100 µg