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This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
CT154; DM domain expressed in testis 1; DM domain expressed in testis protein 1; Dmrt1; DMT1; Doublesex and mab-3 related transcription factor 1; doublesex- and mab-3-related transcription factor 1; Unknown (protein for MGC:134119)
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