DNER Antibodies

Antibodies that detect DNER can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target DNER in Human, Mouse and Rat samples. Our DNER polyclonal, monoclonal and recombinant... Antibodies that detect DNER can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target DNER in Human, Mouse and Rat samples. Our DNER polyclonal, monoclonal and recombinant monoclonal antibodies are developed in... Antibodies that detect DNER can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target DNER in Human, Mouse and Rat samples. Our DNER polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Rat. Find the DNER antibody that fits your needs. Choose from 1 of 14 DNER antibodies, which have been validated in experiments with 1 publication and 13 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the... Antibodies that detect DNER can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target DNER in Human, Mouse and Rat samples. Our DNER polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Rat. Find the DNER antibody that fits your needs. Choose from 1 of 14 DNER antibodies, which have been validated in experiments with 1 publication and 13 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

DNER (Delta-notch-like EGF-related receptor), also known as Delta-notch-like EGF repeat-containing transmembrane protein, is a neuron-specific, atypical Notch ligand expressed in dendrites and cell bodies of neurons throughout the central nervous system. DNER contains ten extracellular EGF-like domains that are highly homologous to those of the Notch ligand, Delta. In the cerebellum, DNER is predominantly expressed in Purkinje cells. DNER mediates neuron-glia interaction during astrocytogenesis through a direct interaction with Notch 1 at Purkinje cell/Bergmann glia contacts. This interaction activates a Deltex-dependent Notch signaling pathway in Bergmann glia and may regulate Bergmann glial morphogenesis. DNER is crucial for the functional and morphological maturation of Bergmann glia. DNER-knockout mice are characterized by motor discoordination and cerebellum retardation in morphogenesis.

同义词

A930026D19Rik; BET; Brain EGF repeat-containing transmembrane protein; Bret; Delta and Notch-like epidermal growth factor-related receptor; delta/notch like EGF repeat containing; delta/notch-like EGF repeat containing; delta/notch-like EGF-related receptor; delta-notch-like EGF repeat-containing transmembrane; Dner; H_NH0150O02.1; LOW QUALITY PROTEIN: delta and Notch-like epidermal growth factor-related receptor; transmembrane protein Bet; UNQ26; UNQ262/PRO299; WUGSC:H_NH0150O02.1

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DNER Antibodies

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