Antibodies that detect E-selectin (CD62E) can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, ELISA and Immunohistochemistry (Frozen). These antibodies target E-selectin (CD62E) in Human, Mouse, Rat, Rabbit and Porcine samples. Our E-selectin (CD62E) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Rabbit, Rat, Mouse, Goat and Sheep. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to E-selectin (CD62E). Find the E-selectin (CD62E) antibody that fits your needs. Choose from 1 of 31 E-selectin (CD62E) antibodies, which have been validated in experiments with 21 publications and 49 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation. This response is immediate and involves a cascade of adhesion receptors. At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade. Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines. In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.
CD62 antigen-like family member E; CD62E; e selectin; E-selectin; ELAM-1; Endothelial leukocyte adhesion molecule 1; LECAM2; Leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2; selectin, endothelial cell