EDA2R Antibodies

Antibodies that detect EDA2R can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target EDA2R in Human, Mouse and Rat samples. Our EDA2R polyclonal, monoclonal and recombinant... Antibodies that detect EDA2R can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target EDA2R in Human, Mouse and Rat samples. Our EDA2R polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit,... Antibodies that detect EDA2R can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target EDA2R in Human, Mouse and Rat samples. Our EDA2R polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the EDA2R antibody that fits your needs. Choose from 1 of 14 EDA2R antibodies, which have been validated in experiments with 18 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen... Antibodies that detect EDA2R can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target EDA2R in Human, Mouse and Rat samples. Our EDA2R polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the EDA2R antibody that fits your needs. Choose from 1 of 14 EDA2R antibodies, which have been validated in experiments with 18 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

X-linked ectodysplasin-A2 receptor (XEDAR) is a recently isolated member of the tumor necrosis factor receptor family that is highly expressed during embryonic development and binds to ectodysplatin-A2 (EDA-A2). Two predominantly expressed isoforms, XEDAR-s and XEDAR-L, differ by only a 21-amino region at the juxtamembrane region of the cytoplasmic domain. Neither isoform possesses a death domain and both have been shown to act mainly through TRAF3 and TRAF6 to activate the NF-kappa-B and JNK pathways. Cells transfected with XEDAR and treated with EDA-A2 cause the assembly of a secondary complex containing FADD, caspase-8 and caspase-10, leading to the activation caspase-8 and caspase-3, and finally apoptosis. The EDA-A2-induced apoptosis is dependent on caspase-9 activation, as various pharmacological and genetic inhibitors of caspase-8 blocked apoptosis following EDA-A2 treatment.

同义词

9430060M22Rik; ectodysplasin A2 isoform receptor; ectodysplasin A2 receptor; EDA2R; EDA-A2 receptor; EDAA2R; EDA-A2R; RGD1564025; Tnfrsf27; Tumor necrosis factor receptor superfamily member 27; tumor necrosis factor receptor superfamily member XEDAR; UNQ2448/PRO5727/PRO34080; X linked ectodysplasin receptor; Xedar; X-linked ectodysplasin-A2 receptor

EDA2R Antibodies

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