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Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase family. The protein encoded by this gene is a receptor for ephrin-B family members.
9330129L11; AW488255; C130099E04Rik; CAPB; Cek5; Cek6; Developmentally-regulated Eph-related tyrosine kinase; Drt; EK5; EK6; ELK; Elkh; ELK-related protein tyrosine kinase; elk-related tyrosine kinase; ENSMUSG00000074119; Eph receptor B1; Eph receptor B2; Eph receptor B2 (ELK-related protein tyrosine kinase); eph tyrosine kinase 2; EPH tyrosine kinase 3; Ephb1; EPHB2; EphB2/CTF1; EphB2/CTF2; EPHB3; EPH-like kinase 5; EPH-like kinase 6; Ephrin B1; Ephrin B2; Ephrin type-B receptor 1; ephrin type-B receptor 2; EphrinB1; EphrinB2; EPHT2; EPHT3; Epth2; Epth3; ERK; ETECK; ETK2; FLJ37986; HEK2; Hek5; Hek6; HEK-6; MGC87492; NET; neural kinase; Neuronally-expressed EPH-related tyrosine kinase; Nuk; Nuk receptor tyrosine kinase; PCBC; Prkm5; protein-tyrosine kinase HEK5; Qek5; Renal carcinoma antigen NY-REN-47; RGD1564232; Sek3; soluble EPHB1 variant 1; Tyro5; TYRO6; Tyrosine-protein kinase receptor EPH-2; tyrosine-protein kinase receptor EPH-3; Tyrosine-protein kinase receptor SEK-3; tyrosine-protein kinase TYRO5
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