Antibodies that detect FOXO4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target FOXO4 in Human, Mouse, Rat and Hamster samples. Our FOXO4 polyclonal, monoclonal,...Antibodies that detect FOXO4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target FOXO4 in Human, Mouse, Rat and Hamster samples. Our FOXO4 polyclonal, monoclonal, recombinant monoclonal and recombinant...Antibodies that detect FOXO4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target FOXO4 in Human, Mouse, Rat and Hamster samples. Our FOXO4 polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown, Relative expression and Cell treatment to confirm specificity to FOXO4. Find the FOXO4 antibody that fits your needs. Choose from 1 of 42 FOXO4 antibodies, which have been validated in experiments with 20 publications and 113 images featured in our data gallery.
Browse primary antibodies for WB, Flow,...
Antibodies that detect FOXO4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target FOXO4 in Human, Mouse, Rat and Hamster samples. Our FOXO4 polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown, Relative expression and Cell treatment to confirm specificity to FOXO4. Find the FOXO4 antibody that fits your needs. Choose from 1 of 42 FOXO4 antibodies, which have been validated in experiments with 20 publications and 113 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
FOXO4 (Forkhead box O4) is encoded by the FOXO4 gene located on the X chromosome. It is also known as AFX1 or MLLT7 (Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Translocated To, 7) and is a member of the O class of forkhead/ winged helix family of transcription factors along with FOXO1, FOXO3 and FOXO6. FOXO4 is abundantly expressed in skeletal muscle and adipose tissue. FOXO4 binds to the Insulin Responsive Element (IRE) and activates downstream targets of Insulin/IGF1 signaling such as IGFBP1. However, the activation of another downstream target of the Insulin/IGF1 pathway, Akt, leads to phosphorylation of FOXO4 on specific Ser/Thr residues. This phosphorylation mediates binding of FOXO4 to 14-3-3 and eventual exit of FOXO4 from the nucleus.
同义词
AFX; Afx1; Afxh; AFXzeta; Fkhr3; Fork head domain transcription factor AFX1; forkhead box O4; forkhead box protein O4; forkhead protein; FOXO4; FOXO4b; MGC120490; MLLT7; myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7; OTTHUMP00000023497; RGD1561201
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