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FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.
1110050J02Rik; 9530073J07Rik; AI851072; FMR1 autosomal homolog 1; fragile X mental retardation autosomal homolog variant p1K; fragile X mental retardation autosomal homolog variant p2K; fragile X mental retardation autosomal homolog variant p4K; fragile X mental retardation autosomal homolog variant p5FK; fragile X mental retardation gene 1, autosomal homolog; fragile X mental retardation gene, autosomal homolog; fragile X mental retardation syndrome-related protein 1; fragile X mental retardation, autosomal homolog 1; fragile X mental retardation-related protein 1; fragile-X-related protein 1; Fxr1; Fxr1h; Fxr1p; hFXR1p; hypothetical protein LOC536793; mFxr1p
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