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Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
AI314904; Glutathione synthase; glutathione synthetase; GS-A/GS-B; GSH S; GSH synthetase; GSHB; GSHS; GSH-S; GSS; HEL-S-64p; HEL-S-88n; MGC14098; OTTHUMP00000030711
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