HDAC8 Antibodies

Antibodies that detect HDAC8 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target HDAC8 in Human, Mouse and Rat samples. Our HDAC8 polyclonal, monoclonal and... Antibodies that detect HDAC8 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target HDAC8 in Human, Mouse and Rat samples. Our HDAC8 polyclonal, monoclonal and recombinant monoclonal antibodies... Antibodies that detect HDAC8 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target HDAC8 in Human, Mouse and Rat samples. Our HDAC8 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown, Knockout and Relative expression to confirm specificity to HDAC8. Find the HDAC8 antibody that fits your needs. Choose from 1 of 34 HDAC8 antibodies, which have been validated in experiments with 30 publications and 70 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other... Antibodies that detect HDAC8 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target HDAC8 in Human, Mouse and Rat samples. Our HDAC8 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown, Knockout and Relative expression to confirm specificity to HDAC8. Find the HDAC8 antibody that fits your needs. Choose from 1 of 34 HDAC8 antibodies, which have been validated in experiments with 30 publications and 70 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Mammalian HDAC8, isolated from human kidney, is a histone deacetylase that shares homology to other HDACs but has different tissue distribution. HDAC8 is localized to the nucleus and plays a role in the development of a broad range of tissues and in the etiology of cancer.

同义词

2610007D20Rik; CDA07; CDLS5; HD8; Hdac8; HDACL1; histone deacetylase 8; histone deacetylase-like 1; MRXS6; RGD1562895; RPD3; WTS

HDAC8 Antibodies

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