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The protein is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway.
C81579; HGPRT; HGPRTase; HPGRT; Hprt; HPRT 1; HPRT B; Hprt1; hprt1 protein; hypoxanthine guanine phosphoribosyl transferase; hypoxanthine guanine phosphoribosyl transferase 1; hypoxanthine phosphoribosyl transferase; hypoxanthine phosphoribosyltransferase 1; hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 1; id:ibd1344; id:ibd5108; testicular tissue protein Li 89; wu:fc10g09; zgc:56221; zgc:86608
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