IFI35 Antibodies

Antibodies that detect IFI35 can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target IFI35 in Human, Mouse, Rat and Porcine samples. Our IFI35 monoclonal, polyclonal and recombinant... Antibodies that detect IFI35 can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target IFI35 in Human, Mouse, Rat and Porcine samples. Our IFI35 monoclonal, polyclonal and recombinant monoclonal antibodies... Antibodies that detect IFI35 can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target IFI35 in Human, Mouse, Rat and Porcine samples. Our IFI35 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the IFI35 antibody that fits your needs. Choose from 1 of 32 IFI35 antibodies, which have been validated in experiments with 2 publications and 71 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody... Antibodies that detect IFI35 can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target IFI35 in Human, Mouse, Rat and Porcine samples. Our IFI35 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the IFI35 antibody that fits your needs. Choose from 1 of 32 IFI35 antibodies, which have been validated in experiments with 2 publications and 71 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

Interferon-Induced Protein 35 (IFI35), encoded by the IFI35 gene, is located on chromosome 17 and is recognized for its role in immune response modulation, especially under viral stress conditions. Structurally, IFI35 is part of a complex regulatory network that influences non-canonical NF-kB signaling. This process involves the proteasomal processing of p105 into the DNA-binding transcription factor p50, which forms a heterodimer with RELB (RELB/p50) to activate cell chemotaxis autonomously. The gene's dynamic expression under viral stress has been linked to various immune regulatory networks and is crucial for immune cell recruitment and maintenance, particularly M2-like tumor-associated macrophages (TAMs) within the tumor microenvironment. IFI35 upregulation is significant in conditions of neuroinflammation and multiple sclerosis, especially in patients treated with interferons (IFN), indicating its potential as a biomolecular marker. Additionally, IFI35's role in triple-negative breast cancer highlights its impact on antitumor immunity, where its ablation enhances the infiltration of effector CD8+ T cells and sensitizes tumors to anti-PD-1 immunotherapy. This positions IFI35 as a key player in both immune response and cancer treatment strategies.

同义词

2010008K16Rik; AW986054; IFI35; ifi-35; IFP 35; IFP35; interferon induced protein 35; interferon-induced 35 kDa protein; Interferon-induced 35 kDa protein homolog; interferon-induced protein 35

IFI35 Antibodies

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