Antibodies that detect JMJD1A can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target JMJD1A in Human, Mouse, Rat and Non-human primate samples. Our JMJD1A polyclonal, monoclonal...Antibodies that detect JMJD1A can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target JMJD1A in Human, Mouse, Rat and Non-human primate samples. Our JMJD1A polyclonal, monoclonal and recombinant monoclonal...Antibodies that detect JMJD1A can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target JMJD1A in Human, Mouse, Rat and Non-human primate samples. Our JMJD1A polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Sheep. Find the JMJD1A antibody that fits your needs. Choose from 1 of 21 JMJD1A antibodies, which have been validated in experiments with 53 publications and 54 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the...
Antibodies that detect JMJD1A can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target JMJD1A in Human, Mouse, Rat and Non-human primate samples. Our JMJD1A polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Sheep. Find the JMJD1A antibody that fits your needs. Choose from 1 of 21 JMJD1A antibodies, which have been validated in experiments with 53 publications and 54 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
JMJD1A is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. JMJD1A is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. It's also Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.
同义词
1700105C21Rik; C230043E16Rik; DKFZp686A24246; DKFZp686P07111; JHDM2a; JHMD2A; JmjC domain-containing histone demethylation protein 2A; Jmjd1; Jmjd1a; jumonji C domain-containing histone demethylase 2A; jumonji domain containing 1A; jumonji domain-containing protein 1A; KDM2A; Kdm3a; Kiaa0742; lysine (K)-specific demethylase 3A; lysine demethylase 3A; lysine-specific demethylase 3A; probable zinc finger protein; testis specific gene A; testis-specific gene A protein; testis-specific protein A; TGSA; Tsga; zinc finger protein TSGA
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