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This gene encodes a potential mitochondrial protein that is a member of the DJ-1/PfpI gene family. This protein is overexpressed in fetal Down syndrome brain. Alternate splicing results in multiple transcript variants.
C21orf33; chromosome 21 open reading frame 33; ES1; ES1 protein homolog, mitochondrial; GATD3A; GATD3B; Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial; Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial; GT335; H KNPH; HES1; human HES1 protein, homolog to E.coli and zebrafish ES1 protein; Keio novel protein I; Keio novel protein-I; KNPH; KNPI; KNP-I; Protein GT335; Protein HES1; testis secretory sperm-binding protein Li 237E
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