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This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.
2210021A15Rik; AB041805; Activator-recruited cofactor 32 kDa component; ARC32; Med8; Mediator complex subunit 8; mediator of RNA polymerase II transcription subunit 8; mediator of RNA polymerase II transcription subunit MED8; mediator of RNA polymerase II transcription, subunit 8 homolog; MGC17544; MGC19641; MNCb-2386; zgc:76877; zgc:76877 protein
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