Antibodies that detect MYBBP1A can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin) and Immunoprecipitation. These antibodies target MYBBP1A in Human, Mouse and Rat samples. Our MYBBP1A polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the MYBBP1A antibody that fits your needs. Choose from 1 of 14 MYBBP1A antibodies, which have been validated in experiments with 2 publications and 26 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
The Myb family of transcription factors, which includes the structurally related A-, B-, and c-Myb genes, regulate differentiation, cellular growth and transactivating gene expression. c-Myb plays an essential role in controlling the proliferation and differentiation of hematopoietic cells, cellular levels of c-Myb decreasing as cells reach terminal differentiation. Myb-binding protein 1A (MYBBP1A) is a novel nuclear protein localized predominantly, but not exclusively, in nucleoli. Although initially isolated as a c-Myb-interacting protein, MYBBP1A is expressed ubiquitously, and associates with a number of different transcription factors. MYBBP1A associates with the aromatic hydrocarbon receptor (AhR), enhancing transactivation and increasing AhR-dependent gene expression. MYBBP1A is a powerful negative regulator of PPAR gamma coactivator 1 alpha (PGC-1 alpha) by p38 MAPK and also acts as a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways.
Myb-binding protein 1A; Myb-binding protein of 160 kDa; nuclear protein P160