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NHE3 (also known as SLC9A3 - Sodium/hydrogen exchanger 3) is a member of the sodium/hydrogen exchanger family that plays a crucial role in acid-base and volume homeostasis by mediating the majority of sodium and bicarbonate reabsorption in the proximal tubule of the kidney. Mutations in the gene can lead to Diarrhea 8.
9030624O13Rik; AI930210; DIAR8; MGC126718; MGC126720; Na(+)/H(+) exchanger 3; Na/H exchanger 3; Na+/H+ exchanger homolog; Na+/H+ exchanger isoform 3; membrane ion exchange protein; Nhe3; NHE-3; NHE-3 antibody; plasma membrane ion transport protein; putative sodium hydrogen exchanger subtype 3; Slc9a3; SLC9A3 antibody; sodium proton exchanger; sodium/hydrogen exchanger; sodium/hydrogen exchanger 3; sodium/hydrogen exchanger isoform 3; Solute carrier family 9 (sodium/hydrogen exchanger 3), antiporter 3, Na+/H+ (amiloride insensitive); solute carrier family 9 (sodium/hydrogen exchanger), isoform 3; solute carrier family 9 (sodium/hydrogen exchanger), member 3; solute carrier family 9 member 3; solute carrier family 9 member A3; solute carrier family 9, member 3; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
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