Antibodies that detect NPC1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target NPC1 in Human, Mouse, Rat, Hamster and Non-human primate samples. Our NPC1 polyclonal,...Antibodies that detect NPC1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target NPC1 in Human, Mouse, Rat, Hamster and Non-human primate samples. Our NPC1 polyclonal, monoclonal and recombinant...Antibodies that detect NPC1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target NPC1 in Human, Mouse, Rat, Hamster and Non-human primate samples. Our NPC1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown and Relative expression to confirm specificity to NPC1. Find the NPC1 antibody that fits your needs. Choose from 1 of 16 NPC1 antibodies, which have been validated in experiments with 28 publications and 47 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP,...
Antibodies that detect NPC1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target NPC1 in Human, Mouse, Rat, Hamster and Non-human primate samples. Our NPC1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown and Relative expression to confirm specificity to NPC1. Find the NPC1 antibody that fits your needs. Choose from 1 of 16 NPC1 antibodies, which have been validated in experiments with 28 publications and 47 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Mutations in the Niemann-Pick disease type C1 (NPC1) gene result in a fatal progressive neurodegenerative disorder characterized by an abnormal sequestration of lipids including cholesterol and glycosphingolipids. The NPC1 protein is a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. NPC1 transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolyzed and released as free cholesterol. NPC1, in addition to FTO, MC4R, and PTER has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations.
同义词
A430089E03Rik; C85354; Cdig2; D18Ertd139e; D18Ertd723e; FLJ98532; I79_014078; lcsd; Niemann Pick type C1; Niemann-Pick C disease protein; niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick type C1; Niemann-Pick type C1 protein; nmf164; NPC; NPC intracellular cholesterol transporter 1; NPC1; sphingomyelinosis; spm; truncated Niemann-Pick C1
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