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PABPC5 encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. PABPC5 is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder.
C820015E17; PABP5; PABP-5; Pabpc5; poly A binding protein, cytoplasmic 5; poly A binding protein, cytoplasmic 5-like; poly(A) binding protein cytoplasmic 5; poly(A) binding protein, cytoplasmic 5; polyadenylate-binding protein 5; polyadenylate-binding protein 5-like
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