Antibodies that detect PERK can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target PERK in Human, Mouse, Rat, Canine and Porcine samples. Our PERK polyclonal, recombinant...Antibodies that detect PERK can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target PERK in Human, Mouse, Rat, Canine and Porcine samples. Our PERK polyclonal, recombinant monoclonal and monoclonal antibodies are...Antibodies that detect PERK can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target PERK in Human, Mouse, Rat, Canine and Porcine samples. Our PERK polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Chicken. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to PERK. Find the PERK antibody that fits your needs. Choose from 1 of 42 PERK antibodies, which have been validated in experiments with 256 publications and 151 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other...
Antibodies that detect PERK can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target PERK in Human, Mouse, Rat, Canine and Porcine samples. Our PERK polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Chicken. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to PERK. Find the PERK antibody that fits your needs. Choose from 1 of 42 PERK antibodies, which have been validated in experiments with 256 publications and 151 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER. Defects in EIF2AK3 are the cause of Wolcott-Rallison syndrome (WRS), also known as multiple epiphyseal dysplasia with early-onset diabetes mellitus. WRS is a rare autosomal recessive disorder, characterized by permanent neonatal or early infancy insulin-dependent diabetes and, at a later age, epiphyseal dysplasia, osteoporosis, growth retardation and other multisystem manifestations, such as hepatic and renal dysfunctions, mental retardation and cardiovascular abnormalities.
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