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The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
25dx; 25-Dx; AA415812; Acidic 25 kDa protein; Dap1; HGNC:16090; HPR6.6; IZA; Lewi; membrane steroid binding protein; membrane-associated progesterone receptor component 1; membrane-bound progesterone receptor; MPR; Pgrmc; Pgrmc1; PPMR; progesterone binding protein; progesterone receptor membrane component 1; steroid membrane binding protein; VEMA; Ventral midline antigen
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