Antibodies that detect PSEN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target PSEN2 in Human, Rat, Mouse and Non-human primate samples. Our PSEN2 polyclonal,...Antibodies that detect PSEN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target PSEN2 in Human, Rat, Mouse and Non-human primate samples. Our PSEN2 polyclonal, recombinant monoclonal and...Antibodies that detect PSEN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target PSEN2 in Human, Rat, Mouse and Non-human primate samples. Our PSEN2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. These antibodies have been verified by Relative expression to confirm specificity to PSEN2. Find the PSEN2 antibody that fits your needs. Choose from 1 of 20 PSEN2 antibodies, which have been validated in experiments with 3 publications and 56 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other...
Antibodies that detect PSEN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target PSEN2 in Human, Rat, Mouse and Non-human primate samples. Our PSEN2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. These antibodies have been verified by Relative expression to confirm specificity to PSEN2. Find the PSEN2 antibody that fits your needs. Choose from 1 of 20 PSEN2 antibodies, which have been validated in experiments with 3 publications and 56 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified.
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