Quinidine Antibodies

Antibodies that detect Quinidine can be used in several scientific applications, including ELISA. Our Quinidine monoclonal and recombinant monoclonal antibodies are developed in Mouse. Find the Quinidine antibody that fits your needs. Choose from 1 of 11 Quinidine antibodies, which have been... Antibodies that detect Quinidine can be used in several scientific applications, including ELISA. Our Quinidine monoclonal and recombinant monoclonal antibodies are developed in Mouse. Find the Quinidine antibody that fits your needs. Choose from 1 of 11 Quinidine antibodies, which have been validated in experiments with 1 image... Antibodies that detect Quinidine can be used in several scientific applications, including ELISA. Our Quinidine monoclonal and recombinant monoclonal antibodies are developed in Mouse. Find the Quinidine antibody that fits your needs. Choose from 1 of 11 Quinidine antibodies, which have been validated in experiments with 1 image featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop... Antibodies that detect Quinidine can be used in several scientific applications, including ELISA. Our Quinidine monoclonal and recombinant monoclonal antibodies are developed in Mouse. Find the Quinidine antibody that fits your needs. Choose from 1 of 11 Quinidine antibodies, which have been validated in experiments with 1 image featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

Quinidine is an alkaloid extracted from the bark of the Cinchona tree with class 1A antiarrhythmic and antimalarial effects. Quinidine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the sodium influx required for the initiation and conduction of impulses resulting in an increase of the threshold for excitation and decreased depolarization during phase 0 of the action potential. In addition, the effective refractory period (ERP), action potential duration (APD), and ERP/APD ratios are increased, resulting in decreased conduction velocity of nerve impulses. Quinidine exerts its antimalarial activity by acting primarily as an intra-erythrocytic schizonticide through association with the heme polymer (hemazoin) in the acidic food vacuole of the parasite thereby preventing further polymerization by heme polymerase enzyme. This results in accumulation of toxic heme and death of the parasite. [National Center for Biotechnology Information. PubChem Compound Database; CID=441074].

同义词

C20H24N2O2; Chinidin; Cin-Quin; Pitayine; Quinidex

Quinidine Antibodies

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