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RDBP is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.
D17H6S45; D6S45; major histocompatibility complex gene RD; negative elongation factor complex member E; negative elongation factor complex member E, Rdbp; negative elongation factor E; negative elongation factor polypeptide E; NELF E; Nelfe; NELF-E; nuclear protein; Rd; RD RNA binding protein; RD RNA-binding protein; RDBP; RDP; RNA-binding protein RD
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