Antibodies that detect RGMA can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target RGMA in Human, Mouse, Rat and Chicken samples. Our RGMA polyclonal, monoclonal and...Antibodies that detect RGMA can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target RGMA in Human, Mouse, Rat and Chicken samples. Our RGMA polyclonal, monoclonal and recombinant monoclonal antibodies are...Antibodies that detect RGMA can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target RGMA in Human, Mouse, Rat and Chicken samples. Our RGMA polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Rat. Find the RGMA antibody that fits your needs. Choose from 1 of 23 RGMA antibodies, which have been validated in experiments with 7 publications and 27 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the...
Antibodies that detect RGMA can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target RGMA in Human, Mouse, Rat and Chicken samples. Our RGMA polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Rat. Find the RGMA antibody that fits your needs. Choose from 1 of 23 RGMA antibodies, which have been validated in experiments with 7 publications and 27 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
同义词
BC059072; C230063O06; repulsive guidance molecule; repulsive guidance molecule A; repulsive guidance molecule family member a; RGM; RGM domain family member A; RGM domain family, member A; RGMA
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