Antibodies that detect SIGLEC8 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGLEC8 in Human, Mouse and Rat samples. Our SIGLEC8 polyclonal, recombinant monoclonal and...Antibodies that detect SIGLEC8 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGLEC8 in Human, Mouse and Rat samples. Our SIGLEC8 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in...Antibodies that detect SIGLEC8 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGLEC8 in Human, Mouse and Rat samples. Our SIGLEC8 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Human, Mouse and Goat. Find the SIGLEC8 antibody that fits your needs. Choose from 1 of 12 SIGLEC8 antibodies, which have been validated in experiments with 4 publications and 17 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to...
Antibodies that detect SIGLEC8 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunocytochemistry. These antibodies target SIGLEC8 in Human, Mouse and Rat samples. Our SIGLEC8 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Human, Mouse and Goat. Find the SIGLEC8 antibody that fits your needs. Choose from 1 of 12 SIGLEC8 antibodies, which have been validated in experiments with 4 publications and 17 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
SIGLEC8 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3-linked sialic acid. and also binds to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC8 is expressed specifically on eosinophils. The protein contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The SIGLEC8 gene belongs to the immunoglobulin superfamily.
同义词
CDw329; MGC59785; SAF2; SAF-2; sialic acid binding Ig like lectin 8; sialic acid binding Ig-like lectin 8; sialic acid-binding Ig-like lectin 8; Sialoadhesin family member 2; Siglec; SIGLEC8; Siglec-8; SIGLEC8L
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