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Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.
2810449N18Rik; AI043036; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; Sir2l6; SIR2-like protein 6; sir2-related protein type 6; Sirt6; sirtuin 6; sirtuin type 6
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