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This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
1700091G21Rik; epididymis secretory sperm binding protein Li 81p; HEL-S-81p; ortholog of human src family associated phosphoprotein 1 SCAP1; pp55; SCAP1; Skap1; Skap55; Skap-55; SKAP55 adapter protein; SKAP55 adaptor protein; src family associated phosphoprotein 1; src family-associated phosphoprotein 1; src kinase associated phosphoprotein 1; src kinase-associated phosphoprotein 1; Src kinase-associated phosphoprotein of 55 kDa
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