Antibodies that detect SKP2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target SKP2 in Human, Mouse, Rat and Non-human primate samples. Our SKP2 polyclonal,...Antibodies that detect SKP2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target SKP2 in Human, Mouse, Rat and Non-human primate samples. Our SKP2 polyclonal, recombinant monoclonal and monoclonal...Antibodies that detect SKP2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target SKP2 in Human, Mouse, Rat and Non-human primate samples. Our SKP2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Sheep. These antibodies have been verified by Cell treatment, Knockdown and Knockout to confirm specificity to SKP2. Find the SKP2 antibody that fits your needs. Choose from 1 of 23 SKP2 antibodies, which have been validated in experiments with 157 publications and 129 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP,...
Antibodies that detect SKP2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target SKP2 in Human, Mouse, Rat and Non-human primate samples. Our SKP2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Sheep. These antibodies have been verified by Cell treatment, Knockdown and Knockout to confirm specificity to SKP2. Find the SKP2 antibody that fits your needs. Choose from 1 of 23 SKP2 antibodies, which have been validated in experiments with 157 publications and 129 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Skp2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex. Skp2 is essential for the G1-S transition in both transformed cells and diploid fibroblasts. Biochemical and genetic experiments have demonstrated that Skp2 is required for the ubiquitination and consequent degradation of p27 in cultured mammalian cells and in vitro reconstitution assays. In normal tissues, Skp2 is expressed in tonsil and placenta. In tumor tissues, Skp2 is expressed widely, in some colon, prostate, pancreas, and skin cancers, with high expression in lung, breast, ovarian, and endometrial cancers. Research suggests that Skp2 plays a role in oncogenesis, particularly in the pathogenesis of lymphomas and breast cancers.
同义词
4930500A04Rik; CDK2/cyclin A-associated protein p45; cyclin A/CDK2-associated protein p45; Cyclin-A/CDK2-associated protein p45; FBL1; F-box protein Skp2; F-box/LRR-repeat protein 1; F-box/WD-40 protein 1; FBXL1; FLB1; FWD1; MGC1366; OTTHUMP00000221389; p45; p45skp2; RGD1562456; Skp2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45); S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
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