Antibodies that detect SMC5 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunoprecipitation and Immunohistochemistry (Paraffin). These antibodies target SMC5 in Human, Mouse and Rat samples. Our SMC5 polyclonal antibodies are developed in Rabbit. These antibodies have been verified by Relative expression to confirm specificity to SMC5. Find the SMC5 antibody that fits your needs. Choose from 1 of 7 SMC5 antibodies, which have been validated in experiments with 1 publication and 17 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; the function seems to be independent of SMC6. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome.
hSMC5; SMC protein 5; SMC-5; SMC5 structural maintenance of chromosomes 5-like 1; Structural maintenance of chromosomes protein 5