Antibodies that detect SPHK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target SPHK1 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our SPHK1 polyclonal,...Antibodies that detect SPHK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target SPHK1 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our SPHK1 polyclonal, monoclonal and...Antibodies that detect SPHK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target SPHK1 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our SPHK1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Rat. These antibodies have been verified by Knockdown and Relative expression to confirm specificity to SPHK1. Find the SPHK1 antibody that fits your needs. Choose from 1 of 38 SPHK1 antibodies, which have been validated in experiments with 52 publications and 80 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA,...
Antibodies that detect SPHK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target SPHK1 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our SPHK1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Rat. These antibodies have been verified by Knockdown and Relative expression to confirm specificity to SPHK1. Find the SPHK1 antibody that fits your needs. Choose from 1 of 38 SPHK1 antibodies, which have been validated in experiments with 52 publications and 80 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer. SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).
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