SPHK2 Antibodies

Antibodies that detect SPHK2 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target SPHK2 in Human, Mouse and Rat samples. Our SPHK2 polyclonal and monoclonal antibodies are... Antibodies that detect SPHK2 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target SPHK2 in Human, Mouse and Rat samples. Our SPHK2 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the... Antibodies that detect SPHK2 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target SPHK2 in Human, Mouse and Rat samples. Our SPHK2 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the SPHK2 antibody that fits your needs. Choose from 1 of 23 SPHK2 antibodies, which have been validated in experiments with 38 publications and 49 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the... Antibodies that detect SPHK2 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target SPHK2 in Human, Mouse and Rat samples. Our SPHK2 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the SPHK2 antibody that fits your needs. Choose from 1 of 23 SPHK2 antibodies, which have been validated in experiments with 38 publications and 49 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer. SPHK2 is an important signaling molecule with intra- and extracellular functions and has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors). These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).

同义词

C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

SPHK2 Antibodies

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