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The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. SRM synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
AA407669; PAPT; Putrescine aminopropyltransferase; SpdST; SPDSY; Spermidine synthase; spermidine synthase-1; SPS1; Srm; SRML1
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