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Heparan sulfate proteoglycans act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
AI467640; AW121680; extracellular sulfatase Sulf-1; FLJ30905; FLJ38022; FLJ41750; hSulf-1; Kiaa1077; mKIAA1077; mSulf-1; RSulfFP1; Sulf1; SULF-1; sulfatase 1; sulfatase FP
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100 µg