Syk Antibodies

Antibodies that detect Syk can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target Syk in Human, Mouse, Rat, Non-human primate and Porcine samples. Our Syk polyclonal,... Antibodies that detect Syk can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target Syk in Human, Mouse, Rat, Non-human primate and Porcine samples. Our Syk polyclonal, monoclonal, recombinant monoclonal and recombinant... Antibodies that detect Syk can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target Syk in Human, Mouse, Rat, Non-human primate and Porcine samples. Our Syk polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression, Cell treatment and Knockout to confirm specificity to Syk. Find the Syk antibody that fits your needs. Choose from 1 of 59 Syk antibodies, which have been validated in experiments with 59 publications and 248 images featured in our data gallery.

Browse primary antibodies... Antibodies that detect Syk can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target Syk in Human, Mouse, Rat, Non-human primate and Porcine samples. Our Syk polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression, Cell treatment and Knockout to confirm specificity to Syk. Find the Syk antibody that fits your needs. Choose from 1 of 59 Syk antibodies, which have been validated in experiments with 59 publications and 248 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases. SYK may also play a role in cancer. Syk translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes. Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases. These kinases also help to activate Syk by phosphorylation of its activation loop.

Synonyms

DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Syk Antibodies

Target Information

Synonyms

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