Antibodies that detect TNFR1 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target TNFR1 in Human, Mouse, Rat, Porcine and Non-human primate samples. Our TNFR1 monoclonal,...Antibodies that detect TNFR1 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target TNFR1 in Human, Mouse, Rat, Porcine and Non-human primate samples. Our TNFR1 monoclonal, polyclonal, recombinant monoclonal and...Antibodies that detect TNFR1 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target TNFR1 in Human, Mouse, Rat, Porcine and Non-human primate samples. Our TNFR1 monoclonal, polyclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse, Armenian Hamster, Rat, Alpaca, Goat and Human. These antibodies have been verified by IP-MS to confirm specificity to TNFR1. Find the TNFR1 antibody that fits your needs. Choose from 1 of 55 TNFR1 antibodies, which have been validated in experiments with 87 publications and 92 images featured in our data gallery.
Browse primary antibodies...
Antibodies that detect TNFR1 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target TNFR1 in Human, Mouse, Rat, Porcine and Non-human primate samples. Our TNFR1 monoclonal, polyclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse, Armenian Hamster, Rat, Alpaca, Goat and Human. These antibodies have been verified by IP-MS to confirm specificity to TNFR1. Find the TNFR1 antibody that fits your needs. Choose from 1 of 55 TNFR1 antibodies, which have been validated in experiments with 87 publications and 92 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors. TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression. The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1). In humans, the TNFR1 gene is located on chromosome 12. Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of TNFR1 were found to be associated with the autosomal dominant periodic fever syndrome, and the impaired receptor clearance is thought to be a mechanism of the disease.
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party
scientific content. Neither the content nor the BenchSci technology and processes for
selection have been evaluated by us; we are providing them as-is and without warranty of any kind,
including for use or application of the Thermo Fisher Scientific products presented.