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This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins.
2900016I08Rik; A730055F12Rik; AU042072; FLJ32746; myb1-like protein 2; Srebf1; target of myb1 like 2 membrane trafficking protein; target of myb1-like 2; target of myb1-like 2 (chicken); Target of Myb-like protein 2; Tom1l2; TOM1-like protein 2; UNQ3124
100 µL
100 µg
100 µL
50 µg