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Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.
2700059D02Rik; beta-actin binding protein betaCAP73; beta-actin-binding protein; BetaCAP73; Kiaa1561; nuclear membrane binding protein; nuclear membrane binding protein NUCLING; nuclear membrane-binding protein; Nucling; RGD1560011; Uaca; uveal autoantigen; uveal autoantigen with coiled coil domains and ankyrin repeats; uveal autoantigen with coiled-coil domains and ankyrin repeats; Uveal autoantigen with coiled-coil domains and ankyrin repeats protein
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